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Harper’S Island

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Harper’S Island

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Exodus - The Theme of Development in Exodus. How it works. Price Calculator. In contrast, people taking a placebo became more sensitive to sunburn.

A separate study identified at least one of the reasons beta- carotene protects against sunburn. Beta- carotene, however, suppressed the activity of the HO-1 gene.

Researchers asked 20 fair-skinned men and women to take Pycnogenol supplements approximately 75 to mg daily for eight weeks. After four weeks the subjects were 40 percent more resistant to sunburn, and after eight weeks they were 84 percent more resistant.

Pycnogenol works partly by reducing the activity of two genes, calgranulin A and B, involved in skin disorders. Although these studies focused only on beta-carotene supplements, it is likely that a multiple-antioxidant supplement or a high-potency multivitamin will work just as well, if not better.

Meanwhile, European researchers have found similar impressive benefits from chamomile-containing creams. One high-quality, reliable brand of chamomile-containing creams and lotions is CamoCare.

This is espe- cially important if you must be outdoors between A. For added protection, take a multivitamin supplement that contains at least some of the antioxidants discussed in this section.

The same idea holds true for your health and risk of disease. One of the ironies we face is that the role of genes in health has often been overstated, whereas the role of nutrition has been greatly undervalued.

The medical promise of genetics and gene therapy has attracted billions of dollars in investments. By comparison, nutrition research receives paltry funding and lacks the allure of high-tech med- icine.

Yet nutrition provides all the basic building blocks of your entire body, and nutrients are essential for normal gene function. They came to this conclusion based on the idea that if some of our genetic traits, such as the color of our eyes, remained the same throughout life, then all of our other genetic traits must stay the same as well.

This view amounts to a form of genetic fatalism, a belief that we cannot change a thing with the genes we inher- ited from our parents.

We can and often do modify our risk of disease. An obese person can lose weight and lower his or her risk for diabetes. A person with a family history of heart dis- ease can change his or her diet and lifestyle and lessen his or her chances of suffering a heart attack.

Doctors routinely tell us that eating better and exercising will reduce our risk of disease. Only recently, however, have they begun to understand that improvements in health are the result of more than just losing weight or controlling cholesterol levels.

Underlying all of these visible improvements in health are more basic changes in gene activity. The lesson in these examples, and in this book as a whole, is that our genes are not rigid.

Rather they constantly respond to the cellular envi- ronment around them. This means that you are anything but powerless when it comes to modifying the activity of your genes.

Because you control what you put into your mouth, you can also control the activity of your genes. The simple act of eating, the most natural of all habits, forces us to make choices.

Again, we can make the best possible decisions or we can squander the opportunity. We can eat fast foods and convenience foods, which are built primarily on sugars, refined carbohydrates, and unhealthy fats.

By doing so we set the stage for abnormal gene activity. This approach fosters normal, even optimal, gene activity.

Everything you do in life is a choice, and doing nothing or delaying a decision for another day is a choice as well. In Feed Your Genes Right, I have provided an explanation and a plan for enhancing your genes and health.

I encourage you to use this information to make the right choices, the ones that build the foundation for a long and healthy life. Knowledge is power.

Use it wisely to promote good health. These are changes you can adopt on your own without any genetic testing. I encourage you to make as many of these changes as pos- sible, just as I have done.

But should you consider genetic testing? Unfortunately, the answer is currently not as straightforward as I would like.

Some medical laboratories provide various degrees of genetic testing. See the list of laboratories later in this appendix.

Unfortunately, many genetic tests remain relatively expensive. Because of this, you and your physician may often do just as well interpreting more common blood tests in terms of their genetic and health implications.

The situation will certainly improve. But such genetic discrimination does not have to occur. I believe that you and I will have a right to obtain genetic testing, assum- ing that the technology is widely available and of reasonable cost.

Knowing of certain genetic risks we face would give us an opportunity to make better dietary, lifestyle, and medical decisions. But there may be a catch.

We live in a society in which insurers of one type or another control the purse strings that pay for medical tests and treatments.

There is a legitimate reason for this concern. Insurers have often appeared arbitrary and unfair in denying approvals or payments for medical care, and it is common for an insurer to deny coverage for a preexisting condition.

For example, if you have been diagnosed with diabetes and then change jobs and insurers, your new insurer may refuse to pay for the treatment of your diabetes.

Like other businesses, insurers are averse to obvious risks or liabilities. So what will probably happen when insurers are asked to pay for your genetic testing, as they inevitably will be?

Just as insurers currently want to learn your medical history, they will undoubtedly want to know the results of your genetic testing.

They want to learn as much as possible to predict the cost of your potential future medical claims. With a predisease you may be denied insurance coverage, or your insurance may exclude coverage for the predisease.

However, there are possible alternative scenarios. A genetic predisposition indicates only risk, not destiny, a key point that is often ignored in discussions of genetics.

You and I were born with various types of genetic risks for disease, and we acquire additional genetic damage that increases our risk of age-related diseases.

Rather than being used as a tool of genetic discrimination, testing, diet, and supplementation can be a way to reduce long-term medical costs.

If there is to be a more rational approach to our future health care, it may be along these lines: Your physician would test you for various genetic predis- positions, as well as for levels of vitamins and other nutrients involved in gene and overall cell function.

She might also recommend certain vitamin supplements. And she would caution you, if you had no obvious genetic predispositions, that you should not be complacent and take your health for granted.

The Upside of Nutrient Testing So, a bit more practically, how can a person determine his or her individual nutritional requirements, which are shaped by a combination of genetics and lifestyle?

It is currently easy and relatively inexpensive to measure blood lev- els of vitamins and minerals, though only nutritionally oriented physicians routinely do this with patients.

Several years ago blood tests found that my levels of vitamin B1 were relatively low. This was odd, because my dietary intake of the vitamin was high, and I had also been taking 50 mg of it as part of a B-complex supplement.

The daily value, or DV, for vitamin B1 is a scant 1. Only after taking an additional mg of vitamin B1 daily more than times the DV for many months did my B1 levels increase to normal.

On another occasion, during a period of extreme personal stress, my right arm became stiff and painful to move for many months.

I had been taking 50 mg of vitamin B6 daily. The DV for B6 is only 1. Again, after consulting a physician, the evidence pointed to an inadequate intake of vitamin B6.

The pain in my arm did not decrease until after I took mg of B6 daily almost times the DV for several months.

It took an entire year for me to regain complete mobility of the arm. This test measures blood levels of various nutrients, including vitamins E and C, beta-carotene, and other nutrients.

A positive test for anti-tTG indicates gluten intolerance, the cause of celiac disease. An extremely sensitive test to assess func- tional vitamin B6 levels.

It measures the activity of an enzyme dependent on B6, instead of just measuring the vitamin. Mutations in these genes are associated with an increased risk of breast and cervical cancer.

A high- sensitivity CRP level of 3. Ideal levels are less than 0. A sensitive test for vitamin B2 that measures the activity of a key antioxidant enzyme that depends on the vitamin.

This mutation indicates either sickle-cell anemia or the less serious sickle-cell trait. Detection of CY and H63D mutations indicates hemochromatosis, an iron-overload disease that increases the risk of dia- betes, heart disease, and premature death.

These tests indicate a genetic predisposition for celiac disease, an intolerance of gluten proteins found in wheat and many other grains.

In fact, insulin levels may be increased years before blood-glucose levels become elevated. The presence of kryptopyrrole in the urine indicates that vitamin B6 and zinc are being excreted at abnormally high rates.

Elevated kryptopyrrole is strongly associated with poor stress responses and an increased risk of mental illness. This cholesterol subfraction may be indicative of an inherited risk of heart disease.

This is a very sensitive test for vitamin B12 levels. A highly sensitive test for vitamin B1. Polymorphisms in the VDR gene interfere with utilization of vitamin D and may increase the risk of osteoporosis, dia- betes, cancer, and multiple sclerosis.

Referral Services for Finding a Nutritionally Oriented Physician The ideal way to assess your overall health and nutritional status is to work with a nutritionally oriented physician.

A physician can order laboratory tests for vitamins, minerals, and other nutrients and help you interpret the results and develop a dietary and supplement plan.

The following organizations pro- vide Internet-based referral services. American College for Advancement in Medicine www.

However, such test- ing is relatively new to the marketplace and can be expensive. It may be just as worthwhile to arrange for more standard and less expensive blood testing of nutrient levels.

Follow-up tests should show whether you have achieved these improvements. Most testing laborato- ries prefer to work with physicians, but some offer home-testing kits.

Your physician may be familiar with other laboratories as well. The companies listed here are known to the author and have particularly high-quality products.

Abkit, Inc. Abkit manufactures and distributes a variety of excellent supplements and cosmetic products. Its AlphaBetic is a well-rounded once-a-day supplement for people with glucose intolerance or diabetes.

For more information call or go to www. Bioforce Bioforce is a venerable Swiss maker of herbal products, with a strong com- mitment to product consistency and quality.

Carlson Laboratories Carlson Laboratories offers the widest selection of natural vitamin E products, as well as a broad range of other vitamin and mineral supplements.

Juvenon Founded by researchers Bruce Ames, Ph. Nutrition 21 Nutrition 21 is the company behind the popular Chromax brand of chromium picolinate, which is also sold under other, more familiar brand names.

For more infor- mation call or go to www. Thorne Research Thorne sells its extensive line of high-quality supplements primarily to physi- cians, but it also accepts orders from consumers.

Their meat departments offer free-range meats. For more information call WILD or go to www. Whole Foods Like Wild Oats, the emphasis at Whole Foods is on wholesome, natural foods, including free-range meats, organic produce, and a wide variety of other healthful food products.

For more information go to www. For more information and the locations of Vitamin Cottage stores, call or go to www.

Specialty Foods CC Pollen If you exercise regularly and intensely, you may require relatively high-carb energy bars.

The princi- pal sweetener in these bars is honey, and they also contain small amounts of bee pollen harvested in southern Arizona.

Many health food stores and Web sites sell Buzz Bars. You can also order them directly from CC Pollen by call- ing or visiting www.

It is located at W. For more information call Among the bars are Apple-Walnut and Cranberry- Orange. Most of the animals are free- range or pasture-fed, so that the meat has a natural balance of fatty acids and less saturated fat than corn-fed beef.

Members of Greatbeef. For information call or go to www. Down syndrome Ottawa, Canada www. Newsletters and Magazines The Nutrition Reporter The Nutrition Reporter is a monthly newsletter, produced by the author, that summarizes recent research on vitamins, minerals, and herbs.

For a sample issue, send a business-size self-addressed envelope, with postage for two ounces, to The Nutrition Reporter, P.

Box , Tuc- son, AZ Sample issues are also available at www. To order call Alternative Medicine As the title suggests, Alternative Medicine is a consumer-oriented maga- zine that focuses on alternative and nonconventional approaches to healing, including vitamin supplements, diet, and energy medicine.

Box , Escondido, CA Rather, it is provided free at leading health food and natural food stores. With a diet program similar to the one in Feed Your Genes Right, this book focuses more on preventing dia- betes and heart disease, as well as losing weight.

Cordain, one of the leading experts on the Paleolithic diet, describes the Pale- olithic diet, which can be considered the original Feed Your Genes Right dietary plan.

Why Grassfed Is Best! This small book pages is worth every penny. It makes a powerful case for eating grass-fed meats and other foods, most of which are compatible with the Feed Your Genes Right dietary plan.

Included is a list of sources for meat from free-range and pasture-fed animals. For more information call during West Coast business hours.

You can also order it from www. Smith provides dietary plans for eating low- grain and no-grain diets. Begley, S. Commoner, B. Kaput, J.

Kim, Y. Moore, D.

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